Cristo Rey De La Salle High School opened its doors on July 9, 2018, to its founding class with the Alpha Summer Institute, a 3-week intensive training program preparing students for their inaugural school year which included an overnight retreat to Saint Mary’s College in Moraga. 

The school is sponsored by the De La Salle Christian Brothers of the Lasallian District of San Francisco New Orleans and is a member of the Cristo Rey Network. The school is accredited by the Western Association of Schools and Colleges and the Western Catholic Educational Association through 2022.